Use of Annexin V based Sperm Selection in Assisted Reproduction

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dc.citation.titleAndrology (Los Angel)es
dc.citation.volume6: 1000182es
dc.creatorTeijeiro, Juan Manuel
dc.creatorMunuce, María José
dc.creatorCaille, Adriana María
dc.creatorZumoffen, Carlos María
dc.creatorMarini, Patricia Estela
dc.date.accessioned2017-11-10T20:38:15Z
dc.date.available2017-11-10T20:38:15Z
dc.date.issued2017-07-07
dc.descriptionInnovative methods to select sperm subpopulations with the best fertilizing ability are needed in assisted reproductive techniques (ART) in order to improve fertilization and pregnancy rates, while also considering possible epigenetic effects on the offspring. Molecular based selection methods are searched for, under the premise that they could be an improvement over classical selection by morphology and movement. One of these methods sustains the elimination of sperm that can bind to annexin A5 (ANX V), coupled to paramagnetic beads, through the phosphatidyl-serine exposed on their membranes upon apoptosis. Although reports accumulate about the use of this method, controversy persists as to the benefits of ANX V based sperm selection in ART. In this review we consider the arguments in favour and against this method and conclude that to the moment the evidence does not support MACS regular use in ART.es
dc.description.filFil: Munuce, María José. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Laboratorio de Medicina Reproductiva; Argentina.es
dc.description.filFil: Teijeiro, Juan Manuel. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Laboratorio de Medicina Reproductiva; Argentina.es
dc.description.filFil: Caille, Adriana María. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Laboratorio de Medicina Reproductiva; Argentina.es
dc.description.filFil: Zumoffen, Carlos María. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Laboratorio de Medicina Reproductiva; Argentina.es
dc.description.filFil: Marini, Patricia Estela. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Laboratorio de Medicina Reproductiva; Argentina.es
dc.formatapplication/pdf
dc.format.extent6: 1000182es
dc.identifier.issn2167-0250es
dc.identifier.urihttp://hdl.handle.net/2133/9267
dc.language.isoenges
dc.publisherOMICS Internationales
dc.relation.publisherversionhttps://www.omicsonline.org/open-access/use-of-annexin-v-based-sperm-selection-in-assisted-reproduction-2167-0250-1000182.php?aid=90816es
dc.rightsopenAccesses
dc.rights.holderMarini, Patricia Estelaes
dc.rights.holderTeijeiro, Juan Manueles
dc.rights.holderMunuce, María Josées
dc.rights.holderCaille, Adriana Maríaes
dc.rights.holderZumoffen, Carlos Maríaes
dc.rights.holderUniversidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas
dc.rights.urihttp://creativecommons.org/publicdomain/zero/1.0/*
dc.subjectAnexina A5es
dc.subjectselección de espermatozoideses
dc.subjecttécnicas de reproducción asistidaes
dc.subjectAnnexin A5es
dc.subjectSperm selectiones
dc.subjectAssisted reproductive techniqueses
dc.titleUse of Annexin V based Sperm Selection in Assisted Reproductiones
dc.typearticle
dc.typeartículo
dc.typepublishedVersion
dc.type.collectionarticulo
dc.type.versionpublishedVersiones

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