Examinando por Autor "Bonghi, Claudio"
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Ítem Acceso Abierto Metabolism of stone fruits: reciprocal contribution between primary metabolism and cell wall(Frontiers Media, 2020-07-09) Canton, Monica; Drincovich, María Fabiana; Lara, María Valeria; Vizzotto, Giannina; Walker, Robert P.; Famiani, Franco; Bonghi, ClaudioÍtem Acceso Abierto Non-structural carbohydrate metabolism in the flesh of Stone fruits of the Genus Prunus (Rosaceae) – a review(Frontiers Media, 2020-11-14) Walker, Robert P.; Battistelli, Alberto; Bonghi, Claudio; Drincovich, María Fabiana; Falchi, Rachele; Lara, María Valeria; Moscatello, Stefano; Vizzotto, Giannina; Famiani, FrancoÍtem Acceso Abierto Stone fruit as biofactories of phytochemicals with potential roles in human nutrition and health(Frontiers Media, 2020-09-02) Lara, María Valeria; Bonghi, Claudio; Famiani, Franco; Vizzotto, Giannina; Walker, Robert P.; Drincovich, María FabianaComprehensive knowledge of the critical properties of the active pharmaceutical ingredients is a requirement within the modern concept of quality. Praziquantel hemihydrate (HH) and monohydrate (MH) are new solid forms of this antihelmintic agent, which have better solubility properties than the commercial anhydrous solid form (polymorph A). The thermal stability of the hydrates was evaluated, aiming to understand any possible transformation (amorphization, change to a less soluble form). Therefore, HH and MH were prepared along with the related anhydrous solid forms A and B, and characterized employing solid-state nuclear magnetic resonance, powder X-ray diffraction, mid and near infrared spectroscopy, thermal methods and the intrinsic dissolution rate. The transformations of HH and MH under thermal stress conditions were monitored through a variable temperature infrared spectroscopy approach, assisted by multivariate curve resolution with alternating least squares (MCR-ALS), finding that HH undergoes a two-step transformation (HH→B→A) to form A, whereas MH dehydrates directly into form A. This was further confirmed by conventional calorimetric methods (differential scanning calorimetry and thermogravimetry) and powder X-ray diffractometry. The impact of changes in the stressed solid forms and their dissolution rates was also assessed. Significant differences in dissolution performance were found regarding the solid forms produced as a consequence of thermally-induced dehydration.Ítem Acceso Abierto Stone fruits: growth and nitrogen and organic acid metabolism in the fruits and seeds—a review(Frontiers Media, 2020-09-25) Famiani, Franco; Bonghi, Claudio; Chen, Zhi-Hui; Drincovich, María Fabiana; Farinelli, Daniela; Lara, María Valeria; Proietti, Simona; Rosati, Adolfo; Vizzotto, Giannina; Walker, Robert P.Ítem Acceso Abierto Sugar metabolism in stone fruit: source-sink relationships and environmental and agronomical effects(Frontiers Media, 2023-11-13) Falchi, Rachele; Bonghi, Claudio; Drincovich, María Fabiana; Famiani, Franco; Lara, María Valeria; Walker, Robert P.; Vizzotto, GianninaThe partitioning of assimilates in fruits, which are economically important sink organs, is ruled by different physiological processes and affected by both environmental and agronomical factors. The bulk of the water and solutes, required for growth, is imported into fruits and seeds through xylem and phloem. In the stone fruits, five vascular bundles enter the base of the fruit, then dividing to supply either the flesh or the seed. The main sugars accumulated in stone fruits include fructose, glucose, and sucrose, along with other minor saccharides. The mechanisms of phloem loading in these fruit species have not been fully elucidated yet, but the available data hint either an apoplastic or a symplastic type or possibly a combination of both, depending on the species and the sugar considered. Similarly, phloem unloading mechanisms, elucidated for a small number of species, depend on genotype and developmental stage. Remarkably, key enzymes and transporters involved in the main sugars-conversion and transport pathways have received considerable attention. In stone fruit trees, the presence of an elevated number of fruits alters the source-sink balance, with a consequent intensification of competition among them and between vegetative and reproductive growth. The main environmental factors affecting this balance and the agronomical/artificial manipulations of source-sink relationships to achieve adequate fruit production and quality are reviewed.