Complete sequence of a blaNDM-1-harboring plasmid in an Acinetobacter bereziniae clinical strain isolated in Argentina

Resumen
The New Delhi metallo-β-lactamase (NDM-1) was initially identified in clinical isolates of Escherichia coli and Klebsiella pneumoniae in Sweden from a patient previously hospitalized in India (1). Since then, blaNDM-1 has been frequently reported in Enterobacteriaceae and Acinetobacter spp. with a fast dissemination in the Indian subcontinent, the Balkan countries, China and the Middle East (2). NDM-1 producers generally associated to Enterobacteriaceae species have also been reported, albeit with much lower frequency, in Latin American countries including Guatemala, Mexico, Colombia and Brazil (3). Moreover, production of NDM-1 in this geographic region has also been noted in A. baumannii in Honduras and Brazil (3, 4), and in A. pittii in Paraguay and Brazil (5, 6). Here, we report the first case of a NDM-1-producing Acinetobacter species in Argentina, an A. bereziniae clinical isolate. We describe also the complete sequence of a blaNDM-1-containing plasmid in this strain.

Palabras clave

NDM, Plasmids, Acinetobacter Bereziniae, Carbapenem Resistance

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