Clinical response in patients with ovarian cancer treated with metronomic chemotherapy

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dc.citation.titleecancermedicalsciencees
dc.citation.volume11es
dc.creatorPerroud, Herman A
dc.creatorScharovsky, O. Graciela
dc.creatorRozados, Viviana R.
dc.creatorAlasino, Carlos María
dc.date.accessioned2018-07-02T15:36:08Z
dc.date.available2018-07-02T15:36:08Z
dc.date.issued2017-02-28
dc.descriptionOvarian cancer (OC) is the leading cause of death from gynaecological cancer. It is extremely hard to diagnose in the early stages and around 70% of patients present with advanced disease. Metronomic chemotherapy (MCT) is described as the chronic administration of, generally low, equally spaced, doses of chemotherapeutic drugs with therapeutic efficacy and low toxicity. This is an effective and low-cost way to treat several types of tumours, including ovarian cancer. Here, we present six cases of advanced ovarian cancer treated with MCT with low doses of cyclophosphamide, which showed clinical response and stable disease.es
dc.description.filFil: Perroud, Herman A. Institute of Experimental Genetics. School of Medical Sciences. National University of Rosario; Rosario; Argentinaes
dc.description.filFil: Scharovsky, Graciela Olga. Universidad Nacional de Rosario. Consejo de Investigaciones UNR, Facultad de Ciencias Médicas; Argentinaes
dc.description.filFil: Rozados, Viviana R. Institute of Experimental Genetics. School of Medical Sciences. National University of Rosario; Rosario; Argentinaes
dc.description.filFil: Alasino, Carlos María. Institute of Oncology of Rosario; Argentinaes
dc.description.sponsorshipFundación Roemmerses
dc.description.sponsorshipMinisterio de Ciencia, Tecnología e Innovación de Santa Fe, Argentina.es
dc.formatapplication/pdf
dc.format.extent1-10es
dc.identifier.issn1754-6605es
dc.identifier.urihttp://hdl.handle.net/2133/11512
dc.language.isoenges
dc.publisherCancer Intelligencees
dc.relation.publisherversionhttps://doi.org/10.3332/ecancer.2017.723es
dc.rightsopenAccesses
dc.rights.holderPerroud et al.; licensee PubMed Centrales
dc.rights.holder© the authors; licensee ecancermedicalsciencees
dc.rights.textThis is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.es
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/ar/*
dc.subjectovarian canceres
dc.subjectmetronomic chemotherapyes
dc.subjectcyclophosphamidees
dc.titleClinical response in patients with ovarian cancer treated with metronomic chemotherapyes
dc.typearticle
dc.typeartículo
dc.typepublishedVersion
dc.type.collectionarticulo
dc.type.versionpublishedVersiones

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CIUNR - Ciencias Naturales - Artículos de Revista
FCM - SCTeI - Artículo de Revista de Investigación