Solid-surface fluorescent properties of estrogens: Green analytical applications

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dc.citation.titleMicrochemical Journalen
dc.citation.volume118
dc.creatorPérez, Rocío Laura
dc.creatorEscandar, Graciela Mónica
dc.date.accessioned2019-02-02T17:02:55Z
dc.date.available2019-02-02T17:02:55Z
dc.date.issued2015-01
dc.descriptionFor the first time, the fluorescent signals produced by 17β-estradiol (E2), estradiol valerate (E2V) and 17α-ethinylestradiol (EE2) were investigated after being retained in selected solid surfaces. Among different studied supports, both C18 and nylon membranes demonstrated to have been able to induce intense signals over their surface, after aqueous solutions of the analytes were retained via a solid-phase extraction procedure. Physicochemical variables which affect the quality of the fluorescence signals were optimized, and the results obtained in the studied solid supports were compared and discussed. While nylon successfully faced the trouble of spectrofluorimetrically quantifying estrogens in pharmaceuticals with unbalanced estrogen/progestagen ratios, C18 membranes showed very good qualities for second-order spectrofluorimeric measurements, allowing the determination of E2 (the most active estrogen) in potentially contaminated fish and chicken samples. The fluorescence excitation–emission matrices, directly measured on a C18 surface, were processed using appropriate chemometric algorithms in order to efficiently quantify E2 in the presence of natural matrix constituents. The present strategy avoids the elution step, considerably decreasing the use of organic solvents, the analysis time and the experimental errors. In addition, the instrumental involved is nonsophisticated and, therefore, the experiments could be carried out in routine laboratories.es
dc.description.filFil: Pérez, Rocío Laura. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario (IQUIR-CONICET); Argentina.es
dc.description.filFil: Escandar, Graciela Mónica. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario (IQUIR-CONICET); Argentina.es
dc.description.sponsorshipUniversidad Nacional de Rosarioes
dc.description.sponsorshipConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET)es
dc.description.sponsorshipAgencia Nacional de Promoción Científica y Tecnológica (ANPCyT), PICT 2010-0084es
dc.formatapplication/pdf
dc.format.extent141-149
dc.identifier.issn0026-265X
dc.identifier.urihttp://hdl.handle.net/2133/13880
dc.language.isoenges
dc.publisherElsevieres
dc.relation.publisherversionhttp://dx.doi.org/doi:10.1016/j.microc.2014.09.003es
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S0026265X14001799?via%3Dihubes
dc.rightsopenAccesses
dc.rights.holderPérez, Rocío Lauraes
dc.rights.holderEscandar, Graciela Mónicaes
dc.rights.holderUniversidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticases
dc.rights.holderElsevieres
dc.rights.textAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)es
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es*
dc.subjectSolid-surface Spectrofluorimetryes
dc.subjectC18 Membraneses
dc.subjectNylon Membraneses
dc.subjectSecond-order Calibrationes
dc.subjectEndocrine Disruptorses
dc.titleSolid-surface fluorescent properties of estrogens: Green analytical applicationses

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