Aquaporins as targets of dietary bioactive phytocompounds

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dc.citation.titleFrontiers in Molecular Bioscienceses
dc.citation.volume5es
dc.creatorTesse, Angela
dc.creatorGrossini, Elena
dc.creatorTamma, Grazia
dc.creatorBrenner, Catherine
dc.creatorPortincasa, Piero
dc.creatorMarinelli, Raúl A.
dc.creatorCalamita, Giuseppe
dc.date.accessioned2021-03-01T17:57:09Z
dc.date.available2021-03-01T17:57:09Z
dc.date.issued2018-04-18
dc.descriptionPlant-derived bioactive compounds have protective role for plants but may also modulate several physiological processes of plant consumers. In the last years, a wide spectrum of phytochemicals have been found to be beneficial to health interacting with molecular signaling pathways underlying critical functions such as cell growth and differentiation, apoptosis, autophagy, inflammation, redox balance, cell volume regulation, metabolic homeostasis, and energy balance. Hence, a large number of biologically active phytocompounds of foods have been isolated, characterized, and eventually modified representing a natural source of novel molecules to prevent, delay or cure several human diseases. Aquaporins (AQPs), a family of membrane channel proteins involved in many body functions, are emerging among the targets of bioactive phytochemicals in imparting their beneficial actions. Here, we provide a comprehensive review of this fast growing topic focusing especially on what it is known on the modulatory effects played by several edible plant and herbal compounds on AQPs, both in health and disease. Phytochemical modulation of AQP expression may provide new medical treatment options to improve the prognosis of several diseases.es
dc.descriptionPara citar este articulo: Tesse A, Grossini E, Tamma G, Brenner C, Portincasa P, Marinelli RA and Calamita G (2018) Aquaporins as Targets of Dietary Bioactive Phytocompounds. Front. Mol. Biosci. 5:30. doi: 10.3389/fmolb.2018.00030
dc.description.filFil: Tesse, Angela. Centre national de la recherche scientifique (CNRS); France.es
dc.description.filFil: Tesse, Angela. Institut National de la Santé et de la Recherche Médicale (INSERM); France.es
dc.description.filFil: Tesse, Angela. Institut du Thorax; France.es
dc.description.filFil: Tesse, Angela. Universitè de Nantes; France.es
dc.description.filFil: Grossini, Elena. University East Piedmont. Department of Translational Medicine. Laboratory of Physiology: Italy.es
dc.description.filFil: Tamma, Grazia. University of Bari “Aldo Moro”. Department of Biosciences, Biotechnologies and Biopharmaceutics; Italy.es
dc.description.filFil: Brenner, Catherine. Université Paris-Sud. LabEx LERMIT; France.es
dc.description.filFil: Brenner, Catherine. Institut National de la Santé et de la Recherche Médicale (INSERM); France.es
dc.description.filFil: Portincasa, Piero. University of Bari “Aldo Moro”. Department of Biomedical Sciences and Human Oncology, Medical School. Clinica Medica “A. Murri”; Italy.es
dc.description.filFil: Marinelli, Raúl A. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Fisiología Experimental (IFISE -CONICET); Argentina.es
dc.description.filFil: Calamita, Giuseppe. University of Bari “Aldo Moro”. Department of Biosciences, Biotechnologies and Biopharmaceutics; Italy.es
dc.formatapplication/pdf
dc.format.extent1-13es
dc.identifier.issn2296-889Xes
dc.identifier.urihttp://hdl.handle.net/2133/19957
dc.language.isoenges
dc.publisherFrontiers Mediaes
dc.relation.publisherversionhttps://doi.org/10.3389/fmolb.2018.00030es
dc.relation.publisherversionhttps://www.frontiersin.org/articles/10.3389/fmolb.2018.00030/fulles
dc.rightsopenAccesses
dc.rights.holderUniversidad Nacional de Rosarioes
dc.rights.holderTesse, Angelaes
dc.rights.holderGrossini, Elenaes
dc.rights.holderTamma, Graziaes
dc.rights.holderBrenner, Catherinees
dc.rights.holderPortincasa, Pieroes
dc.rights.holderMarinelli, Raúl A.es
dc.rights.holderCalamita, Giuseppees
dc.rights.textAttribution 4.0 International (CC BY 4.0)es
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subjectAquaporin Membrane Channelses
dc.subjectFunctional Foodes
dc.subjectNutraceuticses
dc.subjectEpigenomicses
dc.subjectGastrointestinal Microbiomees
dc.subjectAntioxidantses
dc.subjectAnti-Inflammatory Agentses
dc.titleAquaporins as targets of dietary bioactive phytocompoundses
dc.typearticle
dc.typeartículo
dc.typepublishedVersion
dc.type.collectionarticulo
dc.type.versionpublishedVersiones

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