Immobilized boronic acid for Suzuki–Miyaura coupling: application to the generation of pharmacologically relevant molecules
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An synthetic strategy for the generation of a variety of biaryl and related derivatives, based on Suzuki–
Miyaura coupling using immobilized boronic acid, is described. The importance of the methodology was
demonstrated by its further application to biologically interesting compounds such as 4-biaryl-blactams, descripted as cholesterol absorption inhibitors and anti-MRSA active agents, neoflavonoids,
imidazoles, isoxazolines, among others.
This is a post-peer-review, pre-copyedit version of an article published in RSC Advances. The final authenticated version is available online at: https://doi.org/10.1039/c7ra06662g
This is a post-peer-review, pre-copyedit version of an article published in RSC Advances. The final authenticated version is available online at: https://doi.org/10.1039/c7ra06662g
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