Examinando por Autor "Hošnjak, Lea"
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Ítem Acceso Abierto A preliminary study of the virome of the South American Free-Tailed Bats (Tadarida brasiliensis) and identification of two novel mammalian viruses(MDPI, 2020-04-09) Bolatti, Elisa María; Zorec, Tomaž M.; Montani, María E.; Hošnjak, Lea; Chouhy, Diego; Viarengo, Gastón; Casal, Pablo E.; Barquez, Rubén M.; Poljak, Mario; Giri, Adriana Angélica; Irene Villa, German Saigo, Mauricio Taborda, and Violeta Di Domenica, for collecting bat samplesÍtem Acceso Abierto Assessing Gammapapillomavirus infections of mucosal epithelia with two broad-spectrum PCR protocols(BMC, 2020-04-07) Bolatti, Elisa María; Hošnjak, Lea; Chouhy, Diego; Casal, Pablo E.; Re Louhau, María F.; Bottai, Hebe; Komloš , Kristina Fujs; Poljak, Mario; Giri, Adriana Angélica; https://orcid.org/0000-0003-4925-9075Background: Human papillomaviruses (HPVs) have been divided into mucosal and cutaneous types according to their primary epithelial tissue tropism. However, recent studies showed the presence of several cutaneous types in mucosal lesions and healthy mucosa from different anatomical sites. Methods: Here, the HPV prevalence and type-specific distribution were assessed in a variety of mucosal samples from 435 individuals using a combination of two established broad-spectrum primer systems: Gamma-PV PCR and CUT PCR. Results: Overall HPV prevalence in anal canal swabs, cervical cancer biopsies, genital warts and oral swabs was 85, 47, 62 and 4%, respectively. In anal canal swabs, Alpha-PVs were most frequently found (59%), followed by Gamma-(37%) and Beta-PVs (4%). The prevalence and persistence of HPV infection in the anal canal of 226 individuals were further explored. Overall HPV, Gamma-PVs and multiple HPV infections were significantly higher in men vs. women (p = 0.034, p = 0.027 and p = 0.003, respectively); multiple HPV infections were more common in individuals ≤40 years (p = 0.05), and significantly higher prevalence of Gamma-PVs and multiple HPV infections was observed in HIV-1-positive vs. HIV-1-negative individuals (p = 0.003 and p = 0.04, respectively). Out of 21 patients with follow-up anal swabs, only one persistent infection with the same type (HPV58) was detected. Conclusions: Our findings suggest that Gamma-PVs (except species Gamma-6) are ubiquitous viruses with dual muco-cutaneous tissue tropism. Anal canal Gamma-PV infections may be associated with sexual behavior and the host immune status. This study expands the knowledge on Gamma-PVs’ tissue tropism, providing valuable data on the characteristics of HPV infection in the anal canal.Ítem Acceso Abierto Genome announcement : complete genome sequence of a novel Mupapillomavirus, HPV204(Association of Slovenian Dermatovenerologists, 2015) Chouhy, Diego; Bolatti, Elisa María; Giri, Adriana Angélica; Poljak, Mario; Kocjan, Boštjan J.; Šterbenc, Anja; Hošnjak, LeaÍtem Acceso Abierto Molecular characterization, tissue tropism, and genetic variability of the novel Mupapillomavirus type HPV204 and phylogenetically related types HPV1 and HPV63.(PLOS, 2017) Chouhy, Diego; Bolatti, Elisa María; Seme, Katja; Poljak, Mario; Giri, Adriana Angélica; Šterbenc, Anja; Hošnjak, Lea; Oštrbenk, Anja; Kocjan, Boštjan J.; Luzar, BoštjanÍtem Acceso Abierto Viral Metagenomic Data Analyses of Five New World Bat Species from Argentina: Identification of 35 Novel DNA Viruses(MDPI, 2022-01-24) Bolatti, Elisa María; Viarengo, Gastón; Zorec, Tomaž M; Cerri, Agustina; Montani, María E.; Hošnjak, Lea; Casal, Pablo E.; Bortolotto, Eugenia; Di Domenica, Violeta; Chouhy, Diego; Allasia, María Belén; Barquez, Rubén M.; Poljak, Mario; Giri, Adriana Angélica