Matar, PabloAlaniz, LauraRozados, Viviana R.Aquino, Jorge B.Malvicini, MarianaAtorrasagasti, CatalinaGidekel, ManuelSilva, MarceloScharovsky, O. GracielaMazzolini, Guillermo2012-06-122012-06-122009-03-06Matar, Pablo, Laura Alaniz, Viviana Rozados, Jorge B Aquino, Mariana Malvicini, Catalina Atorrasagasti, Manuel Gidekel, Marcelo Silva, O Graciela Scharovsky, and Guillermo Mazzolini. 2009. "Immunotherapy for liver tumors: present status and future prospects". Journal of Biomedical Science. 16 (1).1021-7770http://hdl.handle.net/2133/1910Increasing evidence suggests that immune responses are involved in the control of cancer and that the immune system can be manipulated in different ways to recognize and attack tumors. Progress in immune-based strategies has opened new therapeutic avenues using a number of techniques destined to eliminate malignant cells. In the present review, we overview current knowledge on the importance, successes and difficulties of immunotherapy in liver tumors, including preclinical data available in animal models and information from clinical trials carried out during the lasts years. This review shows that new options for the treatment of advanced liver tumors are urgently needed and that there is a ground for future advances in the field.application/pdfopenAccessarticle© 2009 Matar et al; licensee BioMed Central Ltd.This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.