2026-05-272026-05-272026-04-202771-9693https://hdl.handle.net/2133/33248The objective of this work was to generate and characterize complexes of quinoa proteins (QP) with either resveratrol (RSV)or tocopherol (TOC) whose dimensions fell into the nanoscale. The QP-based nanocomplexes characterization was carried outjointly with encapsulation efficiency determination. Fourier-Transform Infrared Spectroscopy (FTIR) showed no covalent bondformation and indicated that the protein's secondary structure was modified. Transmission Electron Microscopy (TEM) imagesand Dynamic Light Scattering (DLS) measurements confirmed that the addition of bioactive compounds did not substantiallyalter the protein's original size. A consistent particle diameter of 100 nm was observed in both types of nanocomplexes with andwithout RSV and TOC. The antioxidant capacity of nanocomplexes was analyzed after an in vitro simulated digestion process,showing an increase in this property postdigestion. These nanocomplexes hold great potential as functional ingredients.1-8enopenAccessComplexationQuinoa proteinsResveratrolTocopherolarticuloRubinstein, Alejandra J.García Liñares, GuadalupeBoeris, ValeriaPérez, Oscar E.Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y FarmacéuticasAttribution 4.0 International