2024-04-152024-04-1520192041-6539https://hdl.handle.net/2133/26882Dynamic multilevel systems emerged in the last few years as new platforms to study thermodynamic systems. In this work, unprecedented fully communicated three-level systems are studied. First, different conditions were screened to selectively activate thiol/dithioacetal, thiol/thioester, and thiol/disulfide exchanges, individually or in pairs. Some of those conditions were applied, sequentially, to build multilayer dynamic systems wherein information, in the form of relative amounts of building blocks, can be directionally transmitted between different exchange pools. As far as we know, this is the first report of one synthetic dynamic chemical system where relationships between layers can be changed through network operationsenopenAccessDynamic multilevel systemsReversible reactionsDouble-level systemsEngineering multilayer chemical networksarticuloMartínez-Amezaga, MaitenaOrrillo, GastónFurlán, Ricardo Luis EugenioUniversidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y FarmacéuticasAttribution-NonCommercial 4.0 International