Solid-surface fluorescent properties of estrogens: Green analytical applications

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dc.creator Pérez, Rocío Laura
dc.creator Escandar, Graciela Mónica
dc.date.accessioned 2019-02-02T17:02:55Z
dc.date.available 2019-02-02T17:02:55Z
dc.date.issued 2015-01
dc.identifier.issn 0026-265X
dc.identifier.uri http://hdl.handle.net/2133/13880
dc.description For the first time, the fluorescent signals produced by 17β-estradiol (E2), estradiol valerate (E2V) and 17α-ethinylestradiol (EE2) were investigated after being retained in selected solid surfaces. Among different studied supports, both C18 and nylon membranes demonstrated to have been able to induce intense signals over their surface, after aqueous solutions of the analytes were retained via a solid-phase extraction procedure. Physicochemical variables which affect the quality of the fluorescence signals were optimized, and the results obtained in the studied solid supports were compared and discussed. While nylon successfully faced the trouble of spectrofluorimetrically quantifying estrogens in pharmaceuticals with unbalanced estrogen/progestagen ratios, C18 membranes showed very good qualities for second-order spectrofluorimeric measurements, allowing the determination of E2 (the most active estrogen) in potentially contaminated fish and chicken samples. The fluorescence excitation–emission matrices, directly measured on a C18 surface, were processed using appropriate chemometric algorithms in order to efficiently quantify E2 in the presence of natural matrix constituents. The present strategy avoids the elution step, considerably decreasing the use of organic solvents, the analysis time and the experimental errors. In addition, the instrumental involved is nonsophisticated and, therefore, the experiments could be carried out in routine laboratories. es
dc.description.sponsorship Universidad Nacional de Rosario es
dc.description.sponsorship Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) es
dc.description.sponsorship Agencia Nacional de Promoción Científica y Tecnológica (ANPCyT), PICT 2010-0084 es
dc.format application/pdf
dc.format.extent 141-149
dc.language.iso eng es
dc.publisher Elsevier es
dc.rights openAccess es
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es *
dc.subject Solid-surface Spectrofluorimetry es
dc.subject C18 Membranes es
dc.subject Nylon Membranes es
dc.subject Second-order Calibration es
dc.subject Endocrine Disruptors es
dc.title Solid-surface fluorescent properties of estrogens: Green analytical applications es
dc.rights.holder Pérez, Rocío Laura es
dc.rights.holder Escandar, Graciela Mónica es
dc.rights.holder Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas es
dc.rights.holder Elsevier es
dc.relation.publisherversion http://dx.doi.org/doi:10.1016/j.microc.2014.09.003 es
dc.relation.publisherversion https://www.sciencedirect.com/science/article/pii/S0026265X14001799?via%3Dihub es
dc.rights.text Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0) es
dc.citation.title Microchemical Journal en
dc.citation.volume 118
dc.description.fil Fil: Pérez, Rocío Laura. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario (IQUIR-CONICET); Argentina. es
dc.description.fil Fil: Escandar, Graciela Mónica. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario (IQUIR-CONICET); Argentina. es


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